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Leopard (Panthera pardus)
Assassinating leopard over bait is the way it has been done for at least 100 years and there is nothing to it except for the not insignificant subsequent problem of the odd visiting hunter, under the pressure of the moment of truth, due to ingrained indoctrination who instinctively shoots for "centre mass" (common practice in Colorado on deer and the biggest mistake in shot placement dogma - both on animals and felon man) and not into the heart. Please, be kind to your PH and his future life and put the bullet exactly where he had coached you beforehand to break the leopard's heart and not that of his wife and kids. The soft recoiling .308W / 30-06 / 7x57 with heavy soft points are ample.
Leopard are prolific in all hunting areas but are rarely seen. At the new hunting camp I built in Niassa, Mozambique I identified the tracks of four within half a mile either side of camp, heard them "roar" an hour after sunset, heard it nightly catching a baboon but never saw one in my daily - and for reason quite observant - walks when out hunting. Without any doubt my tracker and I have passed within spitting distance of some as we could smell it on a few occasions.
Leopard in the wilds are not known to attack grown men, but a lung shot or gut shot cat will be on a following hunter's back in a blindingly quick attack from mere yards away.
As an update: Many debates have been conducted about the best gun to be used when following a wounded leopard. A double barrel shotgun with any load is good - even a slug - because it is not the supposedly wider shot pattern that favours its use but its rapid pointability. At three yards there is no difference in the diameter of the lead or the impact force of a load of No. 4s or a slug.